Journal article
HSP47: a potential target for fibrotic diseases and implications for therapy
Abstract
Introduction: Chronic fibrotic disorders are challenging clinical problems. The major challenge is the identification of specific targets expressed selectively in fibrotic tissues. Collagen accumulation is the hallmark fibrosis. HSP47 is a collagen-specific chaperon with critical role in collagen folding. This review discusses the anti-fibrotic potential of HSP47. Areas covered: This review compiles data retrieved from the PubMed database with …
Authors
Bellaye P-S; Burgy O; Bonniaud P; Kolb M
Journal
Expert Opinion on Therapeutic Targets, Vol. 25, No. 1, pp. 49–62
Publisher
Taylor & Francis
Publication Date
January 2, 2021
DOI
10.1080/14728222.2021.1861249
ISSN
1472-8222