Journal article
Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016
Abstract
Importance: Clinical trial evidence used to support drug approval is typically the only information on benefits and harms that patients and clinicians can use for decision-making when novel cancer therapies become available. Various evaluations have raised concern about the uncertainty surrounding these data, and a systematic investigation of the available information on treatment outcomes for cancer drugs approved by the US Food and Drug …
Authors
Ladanie A; Schmitt AM; Speich B; Naudet F; Agarwal A; Pereira TV; Sclafani F; Herbrand AK; Briel M; Martin-Liberal J
Journal
JAMA Network Open, Vol. 3, No. 11,
Publisher
American Medical Association (AMA)
Publication Date
November 2, 2020
DOI
10.1001/jamanetworkopen.2020.24406
ISSN
2574-3805