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Journal article

Trial characteristics associated with under‐enrolment of females in randomized controlled trials of heart failure with reduced ejection fraction: a systematic review

Abstract

AIMS: To evaluate temporal trends in the enrolment of females in randomized controlled trials (RCTs) of heart failure with reduced ejection fraction (HFrEF) published in high-impact journals, and assess RCT characteristics associated with under-enrolment. METHODS AND RESULTS: We searched MEDLINE, EMBASE and CINAHL for studies published from January 2000 to May 2019 in journals with impact factor ≥10. We included RCTs that recruited adults with …

Authors

Whitelaw S; Sullivan K; Eliya Y; Alruwayeh M; Thabane L; Yancy CW; Mehran R; Mamas MA; Van Spall HGC

Journal

European Journal of Heart Failure, Vol. 23, No. 1, pp. 15–24

Publisher

Wiley

Publication Date

1 2021

DOI

10.1002/ejhf.2034

ISSN

1388-9842