Journal article
Identification of prognostic factors in childhood T‐cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05‐001 and 11‐001
Abstract
BACKGROUND/OBJECTIVES: While outcomes for pediatric T-cell acute lymphoblastic leukemia (T-ALL) are favorable, there are few widely accepted prognostic factors, limiting the ability to risk stratify therapy.
DESIGN/METHODS: Dana-Farber Cancer Institute (DFCI) Protocols 05-001 and 11-001 enrolled pediatric patients with newly diagnosed B- or T-ALL from 2005 to 2011 and from 2012 to 2015, respectively. Protocol therapy was nearly identical for …
Authors
Burns MA; Place AE; Stevenson KE; Gutiérrez A; Forrest S; Pikman Y; Vrooman LM; Harris MH; Weinberg OK; Hunt SK
Journal
Pediatric Blood & Cancer, Vol. 68, No. 1,
Publisher
Wiley
Publication Date
1 2021
DOI
10.1002/pbc.28719
ISSN
1545-5009
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorChildChild, PreschoolClinical Trials, Phase III as TopicFemaleFollow-Up StudiesHigh-Throughput Nucleotide SequencingHumansInfantMaleNeoplasm, ResidualPrecursor T-Cell Lymphoblastic Leukemia-LymphomaPrognosisRandomized Controlled Trials as TopicRemission InductionRetrospective StudiesSurvival RateYoung Adult