Journal article
Prerandomization run-in periods in randomized controlled trials of chronic diseases: a methodological study
Abstract
OBJECTIVE: To systematically review the epidemiology of prerandomized run-in periods in randomized controlled trials (RCTs) of chronic diseases.
STUDY DESIGN AND SETTING: Meta-epidemiologic study of all RCTs from the four highest impact medical journals from 2011 to 2016. Eligible trials included parallel RCTs that evaluated pharmacologic therapies in adults with chronic diseases with a minimum follow-up of 24 weeks.
Authors
Collister D; Rodrigues JC; Mbuagbaw L; Devereaux PJ; Guyatt G; Herrington W; Walsh M
Journal
Journal of Clinical Epidemiology, Vol. 128, , pp. 148–156
Publisher
Elsevier
Publication Date
12 2020
DOI
10.1016/j.jclinepi.2020.09.035
ISSN
0895-4356