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Prolonging Survival: The Role of Immune Checkpoint...
Journal article

Prolonging Survival: The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive‐Stage Small Cell Lung Cancer

Abstract

BACKGROUND: Small cell lung cancer (SCLC) represents approximately 15% of lung cancers, and approximately 70% are diagnosed as extensive-stage SCLC (ES-SCLC). Although ES-SCLC is highly responsive to chemotherapy, patients typically progress rapidly, and there is an urgent need for new therapies. Immune checkpoint inhibitors (ICIs) have recently been investigated in SCLC, and this review provides guidance on the use of these agents in ES-SCLC …

Authors

Melosky B; Cheema PK; Brade A; McLeod D; Liu G; Price PW; Jao K; Schellenberg DD; Juergens R; Leighl N

Journal

The Oncologist, Vol. 25, No. 11, pp. 981–992

Publisher

Oxford University Press (OUP)

Publication Date

November 1, 2020

DOI

10.1634/theoncologist.2020-0193

ISSN

1083-7159