Global optimization of large-scale MIQCQPs via cluster decomposition: Application to short-term planning of an integrated refinery-petrochemical complex

Integrated refinery-petrochemical facilities are complex systems that require advanced decision-support tools for optimal short-term planning of their operations. The problem can be formulated as a mixed-integer quadratically constrained quadratic program (MIQCQP), in which discrete decisions select operating modes for the process units, while the entire process network is represented by input-output relationships based on bilinear expressions …