Journal article
Association of Factor V Leiden With Subsequent Atherothrombotic Events
Abstract
BACKGROUND: Studies examining the role of factor V Leiden among patients at higher risk of atherothrombotic events, such as those with established coronary heart disease (CHD), are lacking. Given that coagulation is involved in the thrombus formation stage on atherosclerotic plaque rupture, we hypothesized that factor V Leiden may be a stronger risk factor for atherothrombotic events in patients with established CHD.
METHODS: We performed an …
Authors
Mahmoodi BK; Tragante V; Kleber ME; Holmes MV; Schmidt AF; McCubrey RO; Howe LJ; Direk K; Allayee H; Baranova EV
Journal
Circulation, Vol. 142, No. 6, pp. 546–555
Publisher
Wolters Kluwer
Publication Date
August 11, 2020
DOI
10.1161/circulationaha.119.045526
ISSN
0009-7322