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Journal article

Patient-reported outcome instruments used in immune-checkpoint inhibitor clinical trials in oncology: a systematic review

Abstract

ContextImmune-checkpoint inhibitors (ICI) have shown significant benefits for overall survival across various cancer types. Patient-reported outcomes (PROs) are assessed in clinical trials as a measure of efficacy. However, it remains unclear to what extent current PRO instruments capture symptoms specific to ICI toxicities. We conducted a systematic review to identify the use and content validity of PRO instruments in ICI clinical trials in …

Authors

Colomer-Lahiguera S; Bryant-Lukosius D; Rietkoetter S; Martelli L; Ribi K; Fitzpatrick-Lewis D; Sherifali D; Orcurto A; Juergens R; Eicher M

Journal

Journal of Patient-Reported Outcomes, Vol. 4, No. 1,

Publisher

Springer Nature

Publication Date

December 2020

DOI

10.1186/s41687-020-00210-z

ISSN

2509-8020