Antibacterial coatings based on microgels containing quaternary ammonium ions: Modification with polymeric sugars for improved cytocompatibility

The availability of biocompatible, anti-bacterial coatings is of extreme importance for the development of biomedical devices. However, it has proven to be difficult to achieve both biocompatibility and bactericidal properties simultaneously. In the present work, as a novel, alternative approach, a quaternary ammonium salt-based poly(N-isopropylacrylamide) (QAS-PNIPAM) microgel was used both as the bactericidal agent and as an anchor system for …