Journal article
Role of cytoskeleton in isotonic cell volume control of rabbit proximal tubules
Abstract
Stability of mammalian cell volume depends primarily on the sodium pump. When active cation transport of rabbit renal proximal tubules is blocked by ouabain, cells swell, but their size is limited by residual volume control mechanisms. This "ouabain-resistant" volume control is not an active process, as it operates in the presence of cyanide and dinitrophenol and in the absence of exogenous energy. Nevertheless, it remains incompletely …
Authors
Linshaw MA; Macalister TJ; Welling LW; Bauman CA; Hebert GZ; Downey GP; Koo EW; Gotlieb AI
Journal
American Journal of Physiology, Vol. 261, No. 1, pp. f60–f69
Publisher
American Physiological Society
Publication Date
July 1, 1991
DOI
10.1152/ajprenal.1991.261.1.f60
ISSN
0002-9513