Journal article
Relation of Blood Counts during Clozapine Treatment to Serum Concentrations of Clozapine and Nor-Clozapine
Abstract
OBJECTIVE: To determine the relation between serum clozapine and nor-clozapine levels and blood cell counts during clozapine treatment.
METHOD: We undertook a prospective longitudinal study of 37 consecutive patients with a diagnosis of schizophrenia treated with clozapine. We obtained informed consent and then determined serum concentrations of clozapine and nor-clozapine weekly. Clozapine was administered daily in divided doses given every 12 …
Authors
Oyewumi LK; Cernovsky ZZ; Freeman DJ; Streiner DL
Journal
The Canadian Journal of Psychiatry, Vol. 47, No. 3, pp. 257–261
Publisher
SAGE Publications
Publication Date
4 2002
DOI
10.1177/070674370204700306
ISSN
0706-7437