Journal article
The HORIZON Recurrent Fracture Trial: design of a clinical trial in the prevention of subsequent fractures after low trauma hip fracture repair
Abstract
OBJECTIVE: To present the novel design of a trial testing the safety and efficacy of a yearly bisphosponate, zoledronic acid, in preventing new clinical fractures in patients with recent low trauma hip fracture repair.
RESEARCH DESIGN AND METHODS: Randomized, placebo-controlled, triple-blind study. One hundred and fifteen clinical centers worldwide are recruiting approximately 1714 subjects aged 50 years and over (no upper age limit, median age …
Authors
Colón-Emeric CS; Caminis J; Suh TT; Pieper CF; Janning C; Magaziner J; Adachi J; Rosario-Jansen T; Mesenbrink P; Horowitz ZD
Journal
Current Medical Research and Opinion, Vol. 20, No. 6, pp. 903–910
Publisher
Taylor & Francis
Publication Date
June 2004
DOI
10.1185/030079904125003683
ISSN
0300-7995