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The Effect of Temperature and pH on the Stability...
Journal article

The Effect of Temperature and pH on the Stability of Human Pepsin in Stored Gastric Juice: A Method to Prevent Activity Loss

Abstract

The mechanisms controlling pepsin secretion are controversial. A contributory factor may be storage-dependent effects. We have studied the effects of temperature, pH, and storage time on human gastric pepsin. Gastric juice samples taken from three healthy volunteers under both basal and post-pentagastrin-stimulated (6 micrograms/kg subcutaneously) conditions were separated into four aliquots. Each aliquot was titrated to pH 1, 4, or 6 or left …

Authors

De Gara CJ; Burget DW; Sivakumaran T; Hunt RH

Journal

Scandinavian Journal of Gastroenterology, Vol. 21, No. 6, pp. 650–654

Publisher

Taylor & Francis

Publication Date

1 1986

DOI

10.3109/00365528609011096

ISSN

0036-5521