Journal article
The fragility of statistically significant findings from randomized controlled trials in pediatric appendicitis: A systematic review
Abstract
PURPOSE: Randomized controlled trials (RCT) in pediatric appendicitis remain limited, and the robustness of available evidence is unknown. The aim of this study was to determine the fragility of results in pediatric appendicitis RCTs.
METHODS: A systematic search of Embase and MEDLINE was performed. Eligible studies were two-armed RCTs that included at least one statistically significant dichotomous outcome, had parallel-group allocation, and …
Authors
Robinson T; Al-Shahwani N; Easterbrook B; VanHouwelingen L
Journal
Journal of Pediatric Surgery, Vol. 55, No. 5, pp. 800–804
Publisher
Elsevier
Publication Date
5 2020
DOI
10.1016/j.jpedsurg.2020.01.030
ISSN
0022-3468