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The effect of lactate infusion on myocardial...
Journal article

The effect of lactate infusion on myocardial metabolism and ventricular function following ischemia and cardioplegia.

Abstract

Impaired myocardial fatty acid and glucose metabolism following ischemia and cardioplegia may limit the recovery of myocardial oxidative metabolism and ventricular function. Lactate, a simple three carbon compound, can be readily metabolized to pyruvate and is possibly the preferred substrate for aerobic metabolism. Therefore, increasing arterial lactate concentrations may improve myocardial metabolic recovery after ischemia and cardioplegia. …

Authors

Teoh KH; Mickle DA; Weisel RD; Madonik MM; Ivanov J; Harding RD; Romaschin AD; Wilson GJ; Mullen JC

Journal

Canadian Journal of Cardiology, Vol. 6, No. 1, pp. 38–46

Publication Date

1990

ISSN

0828-282X