Journal article
Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study
Abstract
CONTEXT: Epidemiological studies and animal research have suggested that air pollution may negatively impact the central nervous system (CNS). Controlled human exposure studies of the effect of air pollution on the brain have potential to enhance our understanding of this relationship and to inform potential biological mechanisms.
OBJECTIVES: Biomarkers of systemic and CNS inflammation may address whether air pollution exposure induces …
Authors
Cliff R; Curran J; Hirota JA; Brauer M; Feldman H; Carlsten C
Journal
Inhalation Toxicology, Vol. 28, No. 3, pp. 145–153
Publisher
Taylor & Francis
Publication Date
February 23, 2016
DOI
10.3109/08958378.2016.1145770
ISSN
0895-8378
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAir PollutantsBicyclingBiomarkersBrain-Derived Neurotrophic FactorCentral Nervous SystemCross-Over StudiesDouble-Blind MethodFemaleHumansInflammationInhalation ExposureInterleukin-6MaleMiddle AgedNeurotoxicity SyndromesPhosphopyruvate HydrataseS100 Calcium Binding Protein beta SubunitTumor Necrosis Factor-alphaVehicle EmissionsYoung Adult