Indicators of poor neurological prognosis in patients with anoxic coma: a systematic review and critical appraisal of the evidence

Purpose: To determine the neurological clinical signs predicting poor outcome in patients with coma of hypoxic/ anoxic origin through a systematic review and critical appraisal of the literature. Data sources: A structured search was performed using MEDLINE; search terms were 'prognosis' and 'coma'. Study selection: Articles published since 1980 were selected if they studied an adult population, had a sample size greater than 50 patients, …