Safe Prescription of NSAIDs in Clinical Practice

NSAIDs are among the most frequently prescribed medications worldwide and are used in many medical conditions to alleviate pain and inflammation. Their use has continued despite long-known gastrointestinal adverse events and mucosal damage throughout the gastrointestinal tract. The damage is not limited to the upper gastrointestinal tract, and lower gastrointestinal adverse events are as common as those in the upper gastrointestinal tract. …