Antepartum Dalteparin Versus No Antepartum Dalteparin for the Prevention of Pregnancy Complications in Pregnant Women With Thrombophilia (TIPPS)

ABSTRACT Thrombophilias are acquired or genetic predispositions to venous thromboembolism (VTE), which occurs more often in pregnant than in nonpregnant women. Placenta-mediated complications, including preeclampsia, small-for-gestational-age (SGA) infant, placental abruption, or pregnancy loss, are also more common in women with thrombophilia. Whether pregnant women with thrombophilia should receive antepartum thromboprophylaxis remains …