The scavenger receptor class B type I: An HDL receptor involved in lipid transport and HDL dependent signaling

This chapter discusses the significance of the Scavenger Receptor Class B Type I (SR-BI) in high density lipoprotein (HDL) metabolism, atherosclerosis, and coronary heart disease. It also discusses the cellular biology of SR-BI, its activities in lipid transfer between HDL and cells, its role in mediating the activation of cellular signaling pathways by HDL in various cell types, and their possible contribution to atheroprotection. The SR-BI is …