Low power interstitial Nd-YAG laser photocoagulation in normal rabbit brain

The safe, effective, clinical application of interstitial laser irradiation to destroy brain tumour tissue requires a knowledge of the relation of the extent of laser-induced (thermal) necrosis to the delivered laser power and total energy, and to time post-irradiation. We have conducted experiments to determine these relationships in normal rabbit brain. Irradiation by a Nd-YAG laser (1064 nm), at powers of 0.5–3.0 W and exposures of 200–1333 …