Journal article
Circulating mitochondrial DNA in serum of patients with granulomatosis with polyangiitis
Abstract
Neutrophil is a key cell in pathophysiology of granulomatosis with polyangiitis. Recently, neutrophil extracellular traps were described in this disease. Mitochondrial DNA is also released during traps formation. We measured circulating cell-free mitochondrial and genomic DNA in serum of patients with granulomatosis with polyangiitis. Subjects with the disease (14 active and 11 in remission stage) and 10 healthy controls were enrolled. …
Authors
Surmiak MP; Hubalewska-Mazgaj M; Wawrzycka-Adamczyk K; Szczeklik W; Musiał J; Sanak M
Journal
Clinical & Experimental Immunology, Vol. 181, No. 1, pp. 150–155
Publisher
Oxford University Press (OUP)
Publication Date
June 5, 2015
DOI
10.1111/cei.12628
ISSN
0009-9104