Journal article
Cdx2 Polymorphism Affects the Activities of Vitamin D Receptor in Human Breast Cancer Cell Lines and Human Breast Carcinomas
Abstract
Vitamin D plays a role in cancer development and acts through the vitamin D receptor (VDR). It regulates the action of hormone responsive genes and is involved in cell cycle regulation, differentiation and apoptosis. VDR is a critical component of the vitamin D pathway and different common single nucleotide polymorphisms have been identified. Cdx2 VDR polymorphism can play an important role in breast cancer, modulating the activity of VDR. The …
Authors
Pulito C; Terrenato I; Di Benedetto A; Korita E; Goeman F; Sacconi A; Biagioni F; Blandino G; Strano S; Muti P
Journal
PLOS ONE, Vol. 10, No. 4,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0124894
ISSN
1932-6203