Radionuclide Therapy of Bone Metastases

Bone metastases occur in many patients with solid malignancies. Up to 85 % of patients with breast, lung, and prostate cancer at autopsy have bone metastases. Around 80 % of patients with prostate carcinoma, 50 % of patients with breast carcinoma and 40 % of patients with lung carcinoma develop clinically evident osseous metastases. Nearly half of them experience bone pain [1]. Other tumors can also metastasize to bone, including those …