Journal article
Obesity and muscle‐macrophage crosstalk in humans and mice: A systematic review
Abstract
Obesity is associated with the production of inflammatory cytokines that are implicated in insulin resistance (IR), and if not addressed, can lead to type 2 diabetes (T2D). The role of the immune system in skeletal muscle (SM) inflammation and insulin sensitivity is not yet well characterized. As SM IR is an important determinant of glycaemia, it is critical that the muscle-immune phenotype is mapped to help design interventions to target T2D. …
Authors
Rudrapatna S; Bhatt M; Wang K; Bierbrier R; Wang P; Banfield L; Elsheikh W; Sims ED; Peterson D; Thabane L
Journal
Obesity Reviews, Vol. 20, No. 11, pp. 1572–1596
Publisher
Wiley
Publication Date
November 2019
DOI
10.1111/obr.12922
ISSN
1467-7881