Development of homeothermic endothermy is delayed in high-altitude native deer mice (Peromyscus maniculatus)

Altricial mammals begin to independently thermoregulate during the first few weeks of postnatal development. In wild rodent populations, this is also a time of high mortality (50-95%), making the physiological systems that mature during this period potential targets for selection. High altitude (HA) is a particularly challenging environment for small endotherms owing to unremitting low O₂ and ambient temperatures. While superior thermogenic …