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Controlled degradation of low-fouling...
Journal article

Controlled degradation of low-fouling poly(oligo(ethylene glycol)methyl ether methacrylate) hydrogels

Abstract

Degradable low-fouling hydrogels are ideal vehicles for drug and cell delivery. For each application, hydrogel degradation rate must be re-optimized for maximum therapeutic benefit. We developed a method to rapidly and predictably tune degradation rates of low-fouling poly(oligo(ethylene glycol)methyl ether methacrylate) (P(EG) x MA) hydrogels by modifying two interdependent variables: (1) base-catalysed crosslink degradation kinetics, …

Authors

Shoaib MM; Huynh V; Shad Y; Ahmed R; Jesmer AH; Melacini G; Wylie RG

Journal

RSC Advances, Vol. 9, No. 33, pp. 18978–18988

Publisher

Royal Society of Chemistry (RSC)

Publication Date

June 17, 2019

DOI

10.1039/c9ra03441b

ISSN

2046-2069

Labels

Fields of Research (FoR)

McMaster Research Centers and Institutes (RCI)