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Dancing from bottoms up – Roles of the POZ-ZF...
Journal article

Dancing from bottoms up – Roles of the POZ-ZF transcription factor Kaiso in Cancer

Abstract

The POZ-ZF transcription factor Kaiso was discovered two decades ago as a binding partner for p120ctn. Since its discovery, roles for Kaiso in diverse biological processes (epithelial-to-mesenchymal transition, apoptosis, inflammation) and several signalling pathways (Wnt/β-catenin, TGFβ, EGFR, Notch) have emerged. While Kaiso's biological role in normal tissues has yet to be fully elucidated, Kaiso has been increasingly implicated in multiple …

Authors

Pierre CC; Hercules SM; Yates C; Daniel JM

Journal

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Vol. 1871, No. 1, pp. 64–74

Publisher

Elsevier

Publication Date

1 2019

DOI

10.1016/j.bbcan.2018.10.005

ISSN

0304-419X