Frontispiece: DNAzyme Feedback Amplification: Relaying Molecular Recognition to Exponential DNA Amplification

Abstract

A simple but powerful isothermal DNA amplification method, termed DNAzyme feedback amplification (DFA) capable of relaying molecular recognition to exponential DNA amplification is presented. The method incorporates both an RNA‐cleaving DNAzyme (RCD) and rolling circle amplification (RCA) carried out by a special DNA polymerase using a circular DNA template. This method can be used for the detection of both nucleic acid based targets and …