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IN VITRO INHIBITORY EFFECTS OF CHEUBULINIC ACID ON...
Journal article

IN VITRO INHIBITORY EFFECTS OF CHEUBULINIC ACID ON THE CONTRACTILE RESPONSES OF CARDIOVASCULAR MUSCLES

Abstract

1. The effects of chebulinic acid, which has been shown to elicit blood pressure lowering effect in rats, on aortic vascular contraction as well as cardiac contraction were studied in rats. 2. Chebulinic acid had no effect on KCl-induced aortic contraction, but irreversibly inhibited the contractile responses to phenylephrine in an apparently non-competitive manner. Chebulinic acid also inhibited contractile responses of rat aorta to …

Authors

Guan Y; Kwan C; Hsu F; Cheng J

Journal

Clinical and Experimental Pharmacology and Physiology, Vol. 23, No. 8, pp. 747–750

Publisher

Wiley

Publication Date

8 1996

DOI

10.1111/j.1440-1681.1996.tb01771.x

ISSN

0305-1870