Journal article
Autoimmunity as a principal pathogenic factor in the refined model of neuropsychiatric lupus
Abstract
Abstract Objectives: Over the past decades, the MRL mouse model had shown significant validity in elucidating the pathogenesis of neuropsychiatric lupus erythematosus (NP SLE). However, the possibility that the inherited Fas receptor deficiency (and not autoimmunity) accounts for central nervous system (CNS) damage in the original stock 485 of MRL/MpJ‐Fas lpr mice could not be rejected. The aim of the present study was to examine the …
Authors
Loheswaran G; Stanojcic M; Xu L; Sakic B
Journal
Clinical and Experimental Neuroimmunology, Vol. 1, No. 3, pp. 141–152
Publisher
Wiley
Publication Date
September 2010
DOI
10.1111/j.1759-1961.2010.00014.x
ISSN
1759-1961