Journal article
Effects of lorazepam and baclofen on short‐ and long‐latency afferent inhibition
Abstract
KEY POINTS: Short-latency afferent inhibition (SAI) is modulated by GABAA receptor activity, whereas the pharmacological origin of long-latency afferent inhibition remains unknown. This is the first study to report that long-latency afferent inhibition (LAI) is reduced by the GABAA positive allosteric modulator lorazepam, and that both SAI and LAI are not modulated by the GABAB agonist baclofen. These findings advance our understanding of the …
Authors
Turco CV; El‐Sayes J; Locke MB; Chen R; Baker S; Nelson AJ
Journal
The Journal of Physiology, Vol. 596, No. 21, pp. 5267–5280
Publisher
Wiley
Publication Date
11 2018
DOI
10.1113/jp276710
ISSN
0022-3751