Journal article
Antimicrobial Activity of Ceftriaxone Compared with Cefotaxime in the Presence of Serum Albumin
Abstract
The effect of serum albumin on the antimicrobial activity of ceftriaxone, cefotaxime, and a 1:1 ratio of cefotaxime and its desacetyl metabolite against nonpseudomonal Gram-negative bacilli was determined. Antimicrobial activity of drugs was evaluated by measuring minimum inhibitory (mic) and bactericidal (mbc) concentrations in broth with and without human serum albumin. The analysis of logarithmically transformed mean mics and mbcs showed …
Authors
Nath SK; Foster GA; Mandell LA; Rotstein C
Journal
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol. 6, No. 1, pp. 21–27
Publisher
Wiley
Publication Date
1 1995
DOI
10.1155/1995/617610
ISSN
1712-9532