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Characterization of ileal dendritic cell...
Journal article

Characterization of ileal dendritic cell distribution in a rat model of acute and chronic inflammation

Abstract

We examined ileal dendritic cell (DC) subpopulations in a rat model of indomethacin-induced enteritis to determine changes in phenotype and distribution associated with increased mucosal permeability during acute and chronic stages of inflammation. Sprague-Dawley rats were treated with indomethacin (7.5 mg/kg subcutaneously, 2 injections 48 h apart). Animals were killed at day 4 (acute stage) or at day 15 or 30 (chronic stages); control rats …

Authors

Silva MA; Porras M; Jury J; Vergara P; Perdue MH

Journal

Inflammatory Bowel Diseases, Vol. 12, No. 6, pp. 457–470

Publisher

Oxford University Press (OUP)

Publication Date

6 2006

DOI

10.1097/00054725-200606000-00004

ISSN

1078-0998