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Effects of acute exposure to PCBs 126 and 153 on...
Journal article

Effects of acute exposure to PCBs 126 and 153 on anterior pituitary and thyroid hormones and FSH isoforms in adult Sprague Dawley male rats.

Abstract

3,3'4,4',5-Pentachlorobiphenyl (PCB 126) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) were administered to adult male rats in order to identify sensitive indicators of endocrine disruption. We tested the hypothesis that PCB exposure modifies follicle-stimulating hormone (FSH) pituitary isoforms, as well as the pituitary and serum concentrations of FSH, luteinizing hormone (LH), growth hormone, prolactin, and thyroid-stimulating hormone …

Authors

Desaulniers D; Leingartner K; Wade M; Fintelman E; Yagminas A; Foster WG

Journal

Toxicological Sciences, Vol. 47, No. 2, pp. 158–169

Publisher

Oxford University Press (OUP)

Publication Date

February 1, 1999

DOI

10.1093/toxsci/47.2.158

ISSN

1096-6080