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The effect of aspirin on the size of the...
Journal article

The effect of aspirin on the size of the hemostatic plug

Abstract

The prolongation of the bleeding time by aspirin is presumably due to interfering with platelet function. Direct quantitative studies evaluating the effects of aspirin on the platelet component of the hemostatic plug have not been described. We measured blood loss from a standard ear injury in rabbits after treatment with either 5 mg or 200 mg/kg of aspirin (ASA) or sodium salicylate (SA), and related this observation to the number of platelets …

Authors

Kelton JG; Carter CJ

Journal

Thrombosis Research, Vol. 32, No. 3, pp. 267–273

Publisher

Elsevier

Publication Date

11 1983

DOI

10.1016/0049-3848(83)90161-5

ISSN

0049-3848