Journal article
Developing Fluorogenic RNA-Cleaving DNAzymes for Biosensing Applications
Abstract
Deoxyribozymes (or DNAzymes) are single-stranded DNA molecules that have the ability to catalyze a chemical reaction. Currently, DNAzymes have to be isolated from random-sequence DNA libraries by a process known as in vitro selection (IVS) because no naturally occurring DNAzyme has been discovered. Several IVS studies have led to the isolation of many RNA-cleaving DNAzymes (RNase DNAzymes), which catalyze the transesterification of a …
Authors
Ali MM; Aguirre SD; Mok WWK; Li Y
Journal
Methods in Molecular Biology, Vol. 848, , pp. 395–418
Publisher
Springer Nature
Publication Date
2012
DOI
10.1007/978-1-61779-545-9_25
ISSN
1064-3745