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A Versatile Endoribonuclease Mimic Made of DNA:...
Journal article

A Versatile Endoribonuclease Mimic Made of DNA: Characteristics and Applications of the 8–17 RNA‐Cleaving DNAzyme

Abstract

Enzymes play a crucial role in all living organisms by accelerating the rates of a myriad of biochemical reactions that are necessary to sustain life. Although the vast majority of known enzymes are made of protein, in recent years it has become increasingly apparent that other molecular formats, like nucleic acids, can also serve in this capacity. DNAzymes (also known as deoxyribozymes) are synthetic enzymes made of short, single strands of …

Authors

Schlosser K; Li Y

Journal

ChemBioChem, Vol. 11, No. 7, pp. 866–879

Publisher

Wiley

Publication Date

May 3, 2010

DOI

10.1002/cbic.200900786

ISSN

1439-4227