Quadriceps Strength as a Predictor of Knee Osteoarthritis Progression: Sharma L, Dunlop DD, Cahue S, Song J, Hayes KW. Quadriceps strength and osteoarthritis progression in malaligned and lax knees. Ann Intern Med. 2003;138:613–619.

Objective: To determine whether quadriceps strength is associated with tibiofemoral osteoarthritis progression in persons with knee osteoarthritis. The association was examined particularly in malaligned knees and high-laxity knees. Design: Cohort study. Setting: Academic medical center in Chicago, Illinois. Participants: Participants for a natural history study (Mechanical Factors in Arthritis of the Knee) were recruited through periodicals, …