An analysis of Berkson's bias in case-control studies

The bias described by Berkson arises as a mathematical phenomenon, caused by the probabilistic union of different rates of hospitalization for people with different medical phenomena. When the concept is extended to case-control studies, these rates will occur as hd for people with the target disease, he for people with the control condition, and hc for the separate effect of exposure to the suspected etiologic agent. An algebraic analysis of …