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Clinical Trial Design in Acute Lung Injury—Issues...
Journal article

Clinical Trial Design in Acute Lung Injury—Issues and Controversies

Abstract

The evolution of scientific investigation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is replete with examples of effective bench-to-bedside transitions, pioneering research methodology, and international collaboration. This article highlights for clinicians a selection of challenges and controversies of clinical trial design in ALI and ARDS. A section on Patient Selection highlights controversial trade-offs …

Authors

Lamontagne F; Meade M

Journal

Seminars in Respiratory and Critical Care Medicine, Vol. 34, No. 04, pp. 516–521

Publisher

Thieme

Publication Date

8 2013

DOI

10.1055/s-0033-1351120

ISSN

1069-3424