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An animal model of allogeneic donor platelet...
Journal article

An animal model of allogeneic donor platelet refractoriness: the effect of the time of leukodepletion

Abstract

Approximately 50% of multi-transfused individuals become refractory to random donor platelets. Recent clinical data suggest that those patients receiving leukocyte-depleted blood products are less likely to become refractory to random donor platelets than recipients of non- leukocyte-depleted products. Leukocyte depletion can be performed immediately after collection of a unit of whole blood before its storage (prestorage leukodepletion) or …

Authors

Blajchman M; Bardossy L; Carmen R; Goldman M; Heddle N; Singal D

Journal

Blood, Vol. 79, No. 5, pp. 1371–1375

Publisher

American Society of Hematology

Publication Date

March 1, 1992

DOI

10.1182/blood.v79.5.1371.bloodjournal7951371

ISSN

0006-4971