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Methods for the analysis of bleeding outcomes in...
Journal article

Methods for the analysis of bleeding outcomes in randomized trials of PLT transfusion triggers

Abstract

BACKGROUND: A number of methodologic challenges arise in the analysis of bleeding data from clinical trials of PLT transfusion triggers. It is important to understand the assumptions and role of the various methods of analysis to interpret published trials and to design future studies appropriately. STUDY DESIGN AND METHODS: The methods of analysis used for testing the effectiveness and safety of transfusion strategies are reviewed from several …

Authors

Cook RJ; Heddle NM; Rebulla P; Sigouin CS; Webert KE; Transfusion TBEFSTWPOTISFB

Journal

Transfusion, Vol. 44, No. 8, pp. 1135–1142

Publisher

Wiley

Publication Date

August 2004

DOI

10.1111/j.1537-2995.2004.03231.x

ISSN

0041-1132