Journal article
Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis
Abstract
BackgroundHyperuricemia may contribute to renal injury. We do not know whether use of treatments that lower urate reduce the progression of chronic kidney disease (CKD) and cardiovascular disease. We performed a systematic review and meta-analysis of randomized controlled trials to assess the benefits and risks of treatments that lower urate in patients with stages 3-5 CKD.MethodsWe searched MEDLINE, EMBASE, CENTRAL, Web of Science and trial …
Authors
Kanji T; Gandhi M; Clase CM; Yang R
Journal
BMC Nephrology, Vol. 16, No. 1,
Publisher
Springer Nature
Publication Date
12 2015
DOI
10.1186/s12882-015-0047-z
ISSN
1471-2369