Journal article
Idiopathic Pulmonary Fibrosis: From Epithelial Injury to Biomarkers - Insights from the Bench Side
Abstract
Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung disease. Its prognosis is devastating: >50% of the patients die within 3 years after diagnosis. Options for the treatment of IPF are limited and lung transplantation is the only 'curative' therapy. Currently, in the absence of validated indicators of disease progression/activity and diagnostic tools, the clinical management of IPF remains a major …
Authors
Kolb; Borensztajn K; Crestani B; Kolb M
Journal
Respiration, Vol. 86, No. 6, pp. 441–452
Publisher
Karger Publishers
Publication Date
2013
DOI
10.1159/000357598
ISSN
0025-7931
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
BiomarkersBronchoalveolar Lavage FluidEpithelial CellsEpitheliumHumansIdiopathic Pulmonary FibrosisInflammationMatrix Metalloproteinase 1Matrix Metalloproteinase 7Mucin-1OsteopontinPulmonary AlveoliPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated Protein DVascular Endothelial Growth Factor A