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Labelling dendritic cells with SPIO has...
Journal article

Labelling dendritic cells with SPIO has implications for their subsequent in vivo migration as assessed with cellular MRI

Abstract

An optimized non-invasive imaging modality capable of tracking and quantifying in vivo DC migration in patients would provide clinicians with valuable information regarding therapeutic DC-based vaccine outcomes. Superparamagnetic iron oxide (SPIO) nanoparticles were used to label bone marrow-derived DC. In vivo DC migration was tracked and quantified non-invasively using cellular magnetic resonance imaging (MRI) in a mouse model. Labelling DC …

Authors

de Chickera SN; Snir J; Willert C; Rohani R; Foley R; Foster PJ; Dekaban GA

Journal

Contrast Media & Molecular Imaging, Vol. 6, No. 4, pp. 314–327

Publisher

Wiley

Publication Date

7 2011

DOI

10.1002/cmmi.433

ISSN

1555-4309