Journal article
Contrasting effects of HEPES vs HCO3−-buffered media on whole-cell currents in cultured chemoreceptors of the rat carotid body
Abstract
In this study we compared the effects of physiological bicarbonate/CO2-buffered media (BBM) with the commonly used N-2-hydroxyethylpiperazine-N'-2-ethane-sulfonic acid (HEPES)-buffered media (HBM) on whole-cell currents in cultured rat arterial chemoreceptors (i.e. glomus cells) using the perforated-patch technique. Two separate effects were observed on switching from HBM to BBM. First, in the majority of cells tested (31 of 36) there was an …
Authors
Stea A; Nurse CA
Journal
Neuroscience Letters, Vol. 132, No. 2, pp. 239–242
Publisher
Elsevier
Publication Date
11 1991
DOI
10.1016/0304-3940(91)90310-p
ISSN
0304-3940