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Identification of novel catecholamine absorbing...
Journal article

Identification of novel catecholamine absorbing proteins in the central nervous system

Abstract

Several pharmacologically active catecholamines have been shown to react covalently with CNS proteins, namely species of 47, 40, 22, and 20 kDa. Of these, the 47-kDa protein showed the greatest incorporation of tritium following treatment with [3H]dopamine, [3H]ADTN, or [3H]N-propyl-norapomorphine. Labeling was accomplished by incubating the tritiated ligands with crude membrane preparations in the absence of reducing agents. These proteins …

Authors

Ross GM; McCarry BE; Thakur S; Mishra RK

Journal

Journal of Molecular Neuroscience, Vol. 4, No. 3, pp. 141–148

Publisher

Springer Nature

Publication Date

9 1993

DOI

10.1007/bf02782497

ISSN

0895-8696