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miRNA in the Regulation of Skeletal Muscle...
Journal article

miRNA in the Regulation of Skeletal Muscle Adaptation to Acute Endurance Exercise in C57Bl/6J Male Mice

Abstract

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNA species involved in post-transcriptional gene regulation. In vitro studies have identified a small number of skeletal muscle-specific miRNAs which play a crucial role in myoblast proliferation and differentiation. In skeletal muscle, an acute bout of endurance exercise results in the up-regulation of transcriptional networks that regulate mitochondrial biogenesis, glucose and …

Authors

Safdar A; Abadi A; Akhtar M; Hettinga BP; Tarnopolsky MA

Journal

PLOS ONE, Vol. 4, No. 5,

Publisher

Public Library of Science (PLoS)

Publication Date

2009

DOI

10.1371/journal.pone.0005610

ISSN

1932-6203